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Polymorphism of the Fractalkine Receptor CX3CR1 and Systemic Sclerosis-associated Pulmonary Arterial Hypertension

Fractalkine (FKN) and its receptor CX3CR1 are critical mediators in the vascular and tissue damage of several chronic diseases, including systemic sclerosis (SSc) and pulmonary arterial hypertension (PAH). Interestingly, the V249I and T280M genetic polymorphisms influence CX3CR1 expression and funct...

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Detalles Bibliográficos
Autores principales:	Marasini, Bianca, Cossutta, Roberta, Selmi, Carlo, Pozzi, Maria Rosa, Gardinali, Marco, Massarotti, Marco, Erario, Maddalena, Battaglioli, Lodovica, Biondi, Maria Luisa
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270742/ https://www.ncbi.nlm.nih.gov/pubmed/16584113 http://dx.doi.org/10.1080/17402520500303297

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