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p27 Deficiency Cooperates with Bcl-2 but Not Bax to Promote T-Cell Lymphoma
The effect of Bcl-2 on oncogenesis is complex and expression may either delay or accelerate oncogenesis. The pro-oncogenic activity is attributed to its well characterized anti-apoptotic function while the anti-oncogenic function has been attributed to its inhibition of cellular proliferation. Recen...
Autores principales: | Cheng, Ningli, van de Wetering, Christopher I., Knudson, C. Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270898/ https://www.ncbi.nlm.nih.gov/pubmed/18382684 http://dx.doi.org/10.1371/journal.pone.0001911 |
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