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Maternal TLR4 and NOD2 Gene Variants, Pro-Inflammatory Phenotype and Susceptibility to Early-Onset Preeclampsia and HELLP Syndrome
BACKGROUND: Altered maternal inflammatory responses play a role in the development of preeclampsia and the hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. We examined whether allelic variants of the innate immune receptors Toll-like receptor 4 (TLR4) and nucleotide-binding olig...
Autores principales: | van Rijn, Bas B., Franx, Arie, Steegers, Eric A. P., de Groot, Christianne J. M., Bertina, Rogier M., Pasterkamp, Gerard, Voorbij, Hieronymus A. M., Bruinse, Hein W., Roest, Mark |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270909/ https://www.ncbi.nlm.nih.gov/pubmed/18382655 http://dx.doi.org/10.1371/journal.pone.0001865 |
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