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Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
Exposure to ozone, which is a major component of air pollution, induces a form of asthma that occurs in the absence of adaptive immunity. Although ozone-induced asthma is characterized by airway neutrophilia, and not eosinophilia, it is nevertheless associated with airway hyperreactivity (AHR), whic...
Autores principales: | Pichavant, Muriel, Goya, Sho, Meyer, Everett H., Johnston, Richard A., Kim, Hye Y., Matangkasombut, Ponpan, Zhu, Ming, Iwakura, Yoichiro, Savage, Paul B., DeKruyff, Rosemarie H., Shore, Stephanie A., Umetsu, Dale T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271004/ https://www.ncbi.nlm.nih.gov/pubmed/18250191 http://dx.doi.org/10.1084/jem.20071507 |
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