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IL-33 reduces the development of atherosclerosis
Atherosclerosis is a chronic inflammatory disease of the vasculature commonly leading to myocardial infarction and stroke. We show that IL-33, which is a novel IL-1–like cytokine that signals via ST2, can reduce atherosclerosis development in ApoE(−/−) mice on a high-fat diet. IL-33 and ST2 are pres...
Autores principales: | Miller, Ashley M., Xu, Damo, Asquith, Darren L., Denby, Laura, Li, Yubin, Sattar, Naveed, Baker, Andrew H., McInnes, Iain B., Liew, Foo Y. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271006/ https://www.ncbi.nlm.nih.gov/pubmed/18268038 http://dx.doi.org/10.1084/jem.20071868 |
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