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Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells

Mice lacking a functional gene for the Oct2 transcriptional activator display several developmental and functional deficiencies in the B lymphocyte lineage. These include defective B cell receptor (BCR) and Toll-like receptor 4 signaling, an absence of B-1 and marginal zone populations, and globally...

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Detalles Bibliográficos
Autores principales:	Emslie, Dianne, D'Costa, Kathy, Hasbold, Jhagvaral, Metcalf, Donald, Takatsu, Kiyoshi, Hodgkin, Philip O., Corcoran, Lynn M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271016/ https://www.ncbi.nlm.nih.gov/pubmed/18250192 http://dx.doi.org/10.1084/jem.20072049

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