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Toll-Like Receptor Ligands Induce Human T Cell Activation and Death, a Model for HIV Pathogenesis
BACKGROUND: Recently, heightened systemic translocation of microbial products was found in persons with chronic HIV infection and this was linked to immune activation and CD4(+) T cell homeostasis. METHODOLOGY: We examined here the effects of microbial Toll-like receptor (TLR) ligands on T cell acti...
Autores principales: | Funderburg, Nicholas, Luciano, Angel A., Jiang, Wei, Rodriguez, Benigno, Sieg, Scott F., Lederman, Michael M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271052/ https://www.ncbi.nlm.nih.gov/pubmed/18382686 http://dx.doi.org/10.1371/journal.pone.0001915 |
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