Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

Echinocandins are a new generation of novel antifungal agent that inhibit cell wall β(1,3)-glucan synthesis and are normally cidal for the human pathogen Candida albicans. Treatment of C. albicans with low levels of echinocandins stimulated chitin synthase (CHS) gene expression, increased Chs activi...

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Detalles Bibliográficos
Autores principales: Walker, Louise A., Munro, Carol A., de Bruijn, Irene, Lenardon, Megan D., McKinnon, Alastair, Gow, Neil A. R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271054/
https://www.ncbi.nlm.nih.gov/pubmed/18389063
http://dx.doi.org/10.1371/journal.ppat.1000040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271054/
https://www.ncbi.nlm.nih.gov/pubmed/18389063
http://dx.doi.org/10.1371/journal.ppat.1000040

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