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Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

Echinocandins are a new generation of novel antifungal agent that inhibit cell wall β(1,3)-glucan synthesis and are normally cidal for the human pathogen Candida albicans. Treatment of C. albicans with low levels of echinocandins stimulated chitin synthase (CHS) gene expression, increased Chs activi...

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Detalles Bibliográficos
Autores principales:	Walker, Louise A., Munro, Carol A., de Bruijn, Irene, Lenardon, Megan D., McKinnon, Alastair, Gow, Neil A. R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271054/ https://www.ncbi.nlm.nih.gov/pubmed/18389063 http://dx.doi.org/10.1371/journal.ppat.1000040

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