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Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor
G-protein-coupled receptors (GPCRs) respond to external stimuli by activating heterotrimeric G proteins inside the cell. There is increasing evidence that many GPCRs exist as dimers or higher oligomers, but the biochemical nature of such dimers and what roles they have, if any, in signal transductio...
Autores principales: | Mancia, Filippo, Assur, Zahra, Herman, Ariel G, Siegel, Risa, Hendrickson, Wayne A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271072/ https://www.ncbi.nlm.nih.gov/pubmed/18344975 http://dx.doi.org/10.1038/embor.2008.27 |
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