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The effect of stress on the expression of the amyloid precursor protein in rat brain

The abnormal processing of the amyloid precursor protein (APP) is a pivotal event in the development of the unique pathology that defines Alzheimer's disease (AD). Stress, and the associated increase in corticosteroids, appear to accelerate brain ageing and may increase vulnerability to Alzheim...

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Detalles Bibliográficos
Autores principales: Sayer, Rachel, Robertson, Deborah, Balfour, David J.K., Breen, Kieran C., Stewart, Caroline A.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271123/
https://www.ncbi.nlm.nih.gov/pubmed/18178006
http://dx.doi.org/10.1016/j.neulet.2007.11.032