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The effect of stress on the expression of the amyloid precursor protein in rat brain
The abnormal processing of the amyloid precursor protein (APP) is a pivotal event in the development of the unique pathology that defines Alzheimer's disease (AD). Stress, and the associated increase in corticosteroids, appear to accelerate brain ageing and may increase vulnerability to Alzheim...
Autores principales: | Sayer, Rachel, Robertson, Deborah, Balfour, David J.K., Breen, Kieran C., Stewart, Caroline A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Publishers Ireland
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271123/ https://www.ncbi.nlm.nih.gov/pubmed/18178006 http://dx.doi.org/10.1016/j.neulet.2007.11.032 |
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