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Pharmacogenomics of Interferon-ß Therapy in Multiple Sclerosis: Baseline IFN Signature Determines Pharmacological Differences between Patients

BACKGROUND: Multiple sclerosis (MS) is a heterogeneous disease. In order to understand the partial responsiveness to IFNß in Relapsing Remitting MS (RRMS) we studied the pharmacological effects of IFNß therapy. METHODOLOGY: Large scale gene expression profiling was performed on peripheral blood of 1...

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Detalles Bibliográficos
Autores principales:	van Baarsen, Lisa G. M., Vosslamber, Saskia, Tijssen, Marianne, Baggen, Josefien M. C., van der Voort, Laura F., Killestein, Joep, van der Pouw Kraan, Tineke C. T. M., Polman, Chris H., Verweij, Cornelis L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271130/ https://www.ncbi.nlm.nih.gov/pubmed/18382694 http://dx.doi.org/10.1371/journal.pone.0001927

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