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p16(INK4a) Translation Suppressed by miR-24
BACKGROUND: Expression of the tumor suppressor p16(INK4a) increases during aging and replicative senescence. METHODOLOGY/PRINCIPAL FINDINGS: Here, we report that the microRNA miR-24 suppresses p16 expression in human diploid fibroblasts and cervical carcinoma cells. Increased p16 expression with rep...
Autores principales: | Lal, Ashish, Kim, Hyeon Ho, Abdelmohsen, Kotb, Kuwano, Yuki, Pullmann, Rudolf, Srikantan, Subramanya, Subrahmanyam, Ramesh, Martindale, Jennifer L., Yang, Xiaoling, Ahmed, Fariyal, Navarro, Francisco, Dykxhoorn, Derek, Lieberman, Judy, Gorospe, Myriam |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2274865/ https://www.ncbi.nlm.nih.gov/pubmed/18365017 http://dx.doi.org/10.1371/journal.pone.0001864 |
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