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Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation

The micronutrient selenium is present in proteins as selenocysteine (Sec). In eukaryotes and archaea, Sec is formed in a tRNA-dependent conversion of O-phosphoserine (Sep) by O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SepSecS). Here, we present the crystal structure of Methanococcus maripalu...

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Detalles Bibliográficos
Autores principales: Araiso, Yuhei, Palioura, Sotiria, Ishitani, Ryuichiro, Sherrer, R. Lynn, O’Donoghue, Patrick, Yuan, Jing, Oshikane, Hiroyuki, Domae, Naoshi, DeFranco, Julian, Söll, Dieter, Nureki, Osamu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275076/
https://www.ncbi.nlm.nih.gov/pubmed/18158303
http://dx.doi.org/10.1093/nar/gkm1122