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Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein

Minichromosome maintenance (MCM) helicases are the presumptive replicative helicases, thought to separate the two strands of chromosomal DNA during replication. In archaea, the catalytic activity resides within the C-terminal region of the MCM protein. In Methanothermobacter thermautotrophicus the N...

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Detalles Bibliográficos
Autores principales:	Sakakibara, Nozomi, Kasiviswanathan, Rajesh, Melamud, Eugene, Han, Mimi, Schwarz, Frederick P., Kelman, Zvi
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275104/ https://www.ncbi.nlm.nih.gov/pubmed/18184696 http://dx.doi.org/10.1093/nar/gkm1160

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