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Improvement of reporter activity by IRES-mediated polycistronic reporter system

Many in vitro and in vivo applications for transgenesis require co-expression of heterologous genes. The use of internal ribosome entry sites (IRESs) in dicistronic expression vectors enables the expression of two genes controlled by one promoter in target cells or whole organisms. Here we describe...

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Detalles Bibliográficos
Autores principales: Bouabe, Hicham, Fässler, Reinhard, Heesemann, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275123/
https://www.ncbi.nlm.nih.gov/pubmed/18267975
http://dx.doi.org/10.1093/nar/gkm1119