Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair

The cell-cycle inhibitor p21(CDKN1A) has been suggested to directly participate in DNA repair, thanks to the interaction with PCNA. Yet, its role has remained unclear. Among proteins interacting with both p21 and PCNA, the histone acetyltransferase (HAT) p300 has been shown to participate in DNA rep...

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Detalles Bibliográficos
Autores principales: Cazzalini, Ornella, Perucca, Paola, Savio, Monica, Necchi, Daniela, Bianchi, Livia, Stivala, Lucia A., Ducommun, Bernard, Scovassi, A. Ivana, Prosperi, Ennio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275133/
https://www.ncbi.nlm.nih.gov/pubmed/18263614
http://dx.doi.org/10.1093/nar/gkn014

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