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Facile SNP detection using bifunctional, cross-linking oligonucleotide probes

A facile, sensitive method for detecting specific sequences of oligonucleotides was developed. Detection of DNA sequences with single nucleotide discrimination is achieved by combining the selectivity of hybridization with an efficient cross-linking reaction. Readily synthesized bifunctional oligonu...

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Detalles Bibliográficos
Autores principales: Peng, Xiaohua, Greenberg, Marc M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275146/
https://www.ncbi.nlm.nih.gov/pubmed/18281702
http://dx.doi.org/10.1093/nar/gkn052