Cargando…

Probing the mechanism of recognition of ssDNA by the Cdc13-DBD

The Saccharomyces cerevisiae protein Cdc13 tightly and specifically binds the conserved G-rich single-stranded overhang at telomeres and plays an essential role in telomere end-protection and length regulation. The 200 residue DNA-binding domain of Cdc13 (Cdc13-DBD) binds an 11mer single-stranded re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eldridge, Aimee M., Wuttke, Deborah S.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275150/ https://www.ncbi.nlm.nih.gov/pubmed/18250086 http://dx.doi.org/10.1093/nar/gkn017

Ejemplares similares

Details of ssDNA annealing revealed by an HSV-1 ICP8–ssDNA binary complex
por: Tolun, Gökhan, et al.
Publicado: (2013)

Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex
por: Witosch, Justine, et al.
Publicado: (2014)

Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p
por: Zappulla, David C., et al.
Publicado: (2009)

Molecular determinants of the DprA−RecA interaction for nucleation on ssDNA
por: Lisboa, Johnny, et al.
Publicado: (2014)

An ‘open’ structure of the RecOR complex supports ssDNA binding within the core of the complex
por: Radzimanowski, Jens, et al.
Publicado: (2013)

TcaR–ssDNA complex crystal structure reveals new DNA binding mechanism of the MarR family proteins
por: Chang, Yu-Ming, et al.
Publicado: (2014)

Structural transitions during the cooperative assembly of baculovirus single-stranded DNA-binding protein on ssDNA
por: Yin, Jiayi, et al.
Publicado: (2022)

Protein oxidation increases SAMHD1 binding ssDNA via its regulatory site
por: Simermeyer, Theresa L, et al.
Publicado: (2023)

Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization
por: Tripsianes, Konstantinos, et al.
Publicado: (2007)

‘Drc’, a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses
por: Boon, Maarten, et al.
Publicado: (2020)

Crystal structure of DnaT(84–153)-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode
por: Liu, Zheng, et al.
Publicado: (2014)

Surface plasmon resonance imaging reveals multiple binding modes of Agrobacterium transformation mediator VirE2 to ssDNA
por: Kim, Sanghyun, et al.
Publicado: (2015)

RecOR complex including RecR N-N dimer and RecO monomer displays a high affinity for ssDNA
por: Tang, Qun, et al.
Publicado: (2012)

Structure of the human RAD17–RFC clamp loader and 9–1–1 checkpoint clamp bound to a dsDNA–ssDNA junction
por: Day, Matthew, et al.
Publicado: (2022)

Crystal structure of the DdrB/ssDNA complex from Deinococcus radiodurans reveals a DNA binding surface involving higher-order oligomeric states
por: Sugiman-Marangos, Seiji N., et al.
Publicado: (2013)

The Borrelia burgdorferi telomere resolvase, ResT, anneals ssDNA complexed with its cognate ssDNA-binding protein
por: Huang, Shu Hui, et al.
Publicado: (2016)

Structure of mycobacterial 3′-to-5′ RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases
por: Ejaz, Anam, et al.
Publicado: (2018)

Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins
por: Li, Shuangli, et al.
Publicado: (2020)

The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA(+) machine that can switch between oligomeric states
por: Santosh, Vishaka, et al.
Publicado: (2020)

Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome
por: Rossi, Paolo, et al.
Publicado: (2013)

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification
por: Tsai, Kuang-Lei, et al.
Publicado: (2007)

Structures of human TR4(LBD)–JAZF1 and TR4(DBD)–DNA complexes reveal the molecular basis of transcriptional regulation
por: Liu, Yunlong, et al.
Publicado: (2023)

CST does not evict elongating telomerase but prevents initiation by ssDNA binding
por: Zaug, Arthur J, et al.
Publicado: (2021)

ssDNA diffuses along replication protein A via a reptation mechanism
por: Mishra, Garima, et al.
Publicado: (2020)

The telomeric protein Pot1 from Schizosaccharomyces pombe binds ssDNA in two modes with differing 3′ end availability
por: Dickey, Thayne H., et al.
Publicado: (2014)

Computationally exploring the mechanism of bacteriophage T7 gp4 helicase translocating along ssDNA
por: Jin, Shikai, et al.
Publicado: (2022)

Combining use of a panel of ssDNA aptamers in the detection of Staphylococcus aureus
por: Cao, Xiaoxiao, et al.
Publicado: (2009)

Synthesis and incorporation of (13)C-labeled DNA building blocks to probe structural dynamics of DNA by NMR
por: Nußbaumer, Felix, et al.
Publicado: (2017)

BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA
por: Bell, Jason C., et al.
Publicado: (2023)

The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain
por: Lewis, Karen A., et al.
Publicado: (2014)

Mechanochemical regulations of RPA's binding to ssDNA
por: Chen, Jin, et al.
Publicado: (2015)

Acousto-microfluidics for screening of ssDNA aptamer
por: Park, Jee-Woong, et al.
Publicado: (2016)

Biotechnological production of ssDNA with DNA-hydrolyzing deoxyribozymes
por: Liu, Jin, et al.
Publicado: (2021)

Phase separation by ssDNA binding protein controlled via protein−protein and protein−DNA interactions
por: Harami, Gábor M., et al.
Publicado: (2020)

Structure, stability and specificity of the binding of ssDNA and ssRNA with proteins
por: Pal, Arumay, et al.
Publicado: (2019)

Sequence-specific interactions of Rep proteins with ssDNA in the AT-rich region of the plasmid replication origin
por: Wegrzyn, Katarzyna, et al.
Publicado: (2014)

Structural mechanism of DNA recognition by the p204 HIN domain
por: Fan, Xiaojiao, et al.
Publicado: (2021)

Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble
por: Shen, Jiangchuan, et al.
Publicado: (2022)

Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation
por: Wegrzyn, Katarzyna, et al.
Publicado: (2023)

Biostable ssDNA Aptamers Specific for Hodgkin Lymphoma
por: Parekh, Parag, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_d2vijbcp2iglde683g5qrtooon