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Probing the mechanism of recognition of ssDNA by the Cdc13-DBD

The Saccharomyces cerevisiae protein Cdc13 tightly and specifically binds the conserved G-rich single-stranded overhang at telomeres and plays an essential role in telomere end-protection and length regulation. The 200 residue DNA-binding domain of Cdc13 (Cdc13-DBD) binds an 11mer single-stranded re...

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Detalles Bibliográficos
Autores principales:	Eldridge, Aimee M., Wuttke, Deborah S.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275150/ https://www.ncbi.nlm.nih.gov/pubmed/18250086 http://dx.doi.org/10.1093/nar/gkn017

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