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Probing the mechanism of recognition of ssDNA by the Cdc13-DBD
The Saccharomyces cerevisiae protein Cdc13 tightly and specifically binds the conserved G-rich single-stranded overhang at telomeres and plays an essential role in telomere end-protection and length regulation. The 200 residue DNA-binding domain of Cdc13 (Cdc13-DBD) binds an 11mer single-stranded re...
Autores principales: | Eldridge, Aimee M., Wuttke, Deborah S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275150/ https://www.ncbi.nlm.nih.gov/pubmed/18250086 http://dx.doi.org/10.1093/nar/gkn017 |
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