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Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy

PURPOSE: Activation of polyol pathway due to increased aldose reductase (ALR2) activity has been implicated in the development of diabetic complications including diabetic retinopathy (DR), a leading cause of blindness. However, the relationship between hyperglycemia-induced activation of polyol pat...

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Detalles Bibliográficos
Autores principales: Reddy, G. Bhanuprakash, Satyanarayana, A., Balakrishna, N., Ayyagari, Radha, Padma, M., Viswanath, K., Petrash, J. Mark
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275210/
https://www.ncbi.nlm.nih.gov/pubmed/18385795