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Intragraft gene expression profile associated with the induction of tolerance

BACKGROUND: Xenotransplantation holds the promise of providing an unlimited supply of donor organs for terminal patients with organ failure. Pre-existing natural antibodies to the Galα1,3Galβ1,4GlcNac-R (αGal) carbohydrate xenoantigen, however, bind rapidly to the graft endothelium and initiate hype...

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Detalles Bibliográficos
Autores principales: Doki, Tomoko, Mello, Michael, Mock, Dennis, Evans, Jacqueline M, Kearns-Jonker, Mary
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275216/
https://www.ncbi.nlm.nih.gov/pubmed/18267024
http://dx.doi.org/10.1186/1471-2172-9-5