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PITX2 gain-of-function induced defects in mouse forelimb development
BACKGROUND: Limb development and patterning originate from a complex interplay between the skeletal elements, tendons, and muscles of the limb. One of the genes involved in patterning of limb muscles is the homeobox transcription factor Pitx2 but its role in forelimb development is uncharacterized....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275225/ https://www.ncbi.nlm.nih.gov/pubmed/18312615 http://dx.doi.org/10.1186/1471-213X-8-25 |