Negative Correlation between Brain Glutathione Level and Negative Symptoms in Schizophrenia: A 3T (1)H-MRS Study

BACKGROUND: Glutathione (GSH), a major intracellular antioxidant, plays a role in NMDA receptor-mediated neurotransmission, which is involved in the pathophysiology of schizophrenia. In the present study, we aimed to investigate whether GSH levels are altered in the posterior medial frontal cortex o...

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Detalles Bibliográficos
Autores principales: Matsuzawa, Daisuke, Obata, Takayuki, Shirayama, Yukihiko, Nonaka, Hiroi, Kanazawa, Yoko, Yoshitome, Eiji, Takanashi, Junichi, Matsuda, Tsuyoshi, Shimizu, Eiji, Ikehira, Hiroo, Iyo, Masaomi, Hashimoto, Kenji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275307/
https://www.ncbi.nlm.nih.gov/pubmed/18398470
http://dx.doi.org/10.1371/journal.pone.0001944

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