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Effect of ionic strength and presence of serum on lipoplexes structure monitorized by FRET
BACKGROUND: Serum and high ionic strength solutions constitute important barriers to cationic lipid-mediated intravenous gene transfer. Preparation or incubation of lipoplexes in these media results in alteration of their biophysical properties, generally leading to a decrease in transfection effici...
Autores principales: | Madeira, Catarina, Loura, Luís MS, Prieto, Manuel, Fedorov, Aleksander, Aires-Barros, M Raquel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275333/ https://www.ncbi.nlm.nih.gov/pubmed/18302788 http://dx.doi.org/10.1186/1472-6750-8-20 |
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