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IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection
Therapeutic vaccination is a potentially powerful strategy to establish immune control and eradicate persistent viral infections. Large and multifunctional antiviral T cell responses are associated with control of viral persistence; however, for reasons that were mostly unclear, current therapeutic...
Autores principales: | Brooks, David G., Lee, Andrew M., Elsaesser, Heidi, McGavern, Dorian B., Oldstone, Michael B.A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275377/ https://www.ncbi.nlm.nih.gov/pubmed/18332180 http://dx.doi.org/10.1084/jem.20071948 |
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