Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection

Therapeutic vaccination is a potentially promising strategy to enhance T cell immunity and viral control in chronically infected individuals. However, therapeutic vaccination approaches have fallen short of expectations, and effective boosting of antiviral T cell responses has not always been observ...

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Detalles Bibliográficos
Autores principales: Ha, Sang-Jun, Mueller, Scott N., Wherry, E. John, Barber, Daniel L., Aubert, Rachael D., Sharpe, Arlene H., Freeman, Gordon J., Ahmed, Rafi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275378/
https://www.ncbi.nlm.nih.gov/pubmed/18332181
http://dx.doi.org/10.1084/jem.20071949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275378/
https://www.ncbi.nlm.nih.gov/pubmed/18332181
http://dx.doi.org/10.1084/jem.20071949

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