Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase

We report the results of studies in which partially purified centrosomes, nuclei, and DNA were injected into frog's eggs, which are naturally arrested in metaphase or interphase. These results have led to an independent assessment of the contributions of the centrosome and the chromatin to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Karsenti, E., Newport, J., Kirschner, M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1984
Materias:
Supplement: The Cytoplasmic Matrix and the Integration of Cellular Function
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275591/
https://www.ncbi.nlm.nih.gov/pubmed/6235234
_version_ 1782151878482591744
author Karsenti, E.
Newport, J.
Kirschner, M.
author_facet Karsenti, E.
Newport, J.
Kirschner, M.
author_sort Karsenti, E.
collection PubMed
description We report the results of studies in which partially purified centrosomes, nuclei, and DNA were injected into frog's eggs, which are naturally arrested in metaphase or interphase. These results have led to an independent assessment of the contributions of the centrosome and the chromatin to the formation of the mitotic spindle and suggest a simple explanation for the transition from interphase to metaphase microtubule arrays.
format Text
id pubmed-2275591
institution National Center for Biotechnology Information
language English
publishDate 1984
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-22755912008-05-01 Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase Karsenti, E. Newport, J. Kirschner, M. J Cell Biol Supplement: The Cytoplasmic Matrix and the Integration of Cellular Function We report the results of studies in which partially purified centrosomes, nuclei, and DNA were injected into frog's eggs, which are naturally arrested in metaphase or interphase. These results have led to an independent assessment of the contributions of the centrosome and the chromatin to the formation of the mitotic spindle and suggest a simple explanation for the transition from interphase to metaphase microtubule arrays. The Rockefeller University Press 1984-07-01 /pmc/articles/PMC2275591/ /pubmed/6235234 Text en Copyright © 1984, This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Supplement: The Cytoplasmic Matrix and the Integration of Cellular Function
Karsenti, E.
Newport, J.
Kirschner, M.
Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
title Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
title_full Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
title_fullStr Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
title_full_unstemmed Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
title_short Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
title_sort respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase
topic Supplement: The Cytoplasmic Matrix and the Integration of Cellular Function
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275591/
https://www.ncbi.nlm.nih.gov/pubmed/6235234
work_keys_str_mv AT karsentie respectiverolesofcentrosomesandchromatinintheconversionofmicrotubulearraysfrominterphasetometaphase
AT newportj respectiverolesofcentrosomesandchromatinintheconversionofmicrotubulearraysfrominterphasetometaphase
AT kirschnerm respectiverolesofcentrosomesandchromatinintheconversionofmicrotubulearraysfrominterphasetometaphase

Ejemplares similares