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Comparative modelling by restraint-based conformational sampling
BACKGROUND: Although comparative modelling is routinely used to produce three-dimensional models of proteins, very few automated approaches are formulated in a way that allows inclusion of restraints derived from experimental data as well as those from the structures of homologues. Furthermore, prot...
Autores principales: | Furnham, Nicholas, de Bakker, Paul IW, Gore, Swanand, Burke, David F, Blundell, Tom L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275734/ https://www.ncbi.nlm.nih.gov/pubmed/18237407 http://dx.doi.org/10.1186/1472-6807-8-7 |
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