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Comparative modelling by restraint-based conformational sampling

BACKGROUND: Although comparative modelling is routinely used to produce three-dimensional models of proteins, very few automated approaches are formulated in a way that allows inclusion of restraints derived from experimental data as well as those from the structures of homologues. Furthermore, prot...

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Detalles Bibliográficos
Autores principales: Furnham, Nicholas, de Bakker, Paul IW, Gore, Swanand, Burke, David F, Blundell, Tom L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275734/
https://www.ncbi.nlm.nih.gov/pubmed/18237407
http://dx.doi.org/10.1186/1472-6807-8-7

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