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Analysis of Beta-Tubulin Gene Exon 4 Mutations in Advanced Stage III or IV Gastric Cancer
The mechanisms that cause chemoresistance of gastric cancer have yet to be elucidated. Taxanes and promising agents that were recently approved for treatment of advanced or recurrent gastric cancer. Mutations of beta-tubulin, which is a target of taxianes, have been shown to confer chemoresistance a...
Autores principales: | Tahara, Tomomitsu, Arisawa, Tomiyasu, Shibata, Tomoyuki, Hirata, Ichiro, Nakano, Hiroshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275766/ https://www.ncbi.nlm.nih.gov/pubmed/18398498 http://dx.doi.org/10.3164/jcbn.40.210 |
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