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Molecular and Cellular Basis of Microvascular Perfusion Deficits Induced by Clostridium perfringens and Clostridium septicum
Reduced tissue perfusion leading to tissue ischemia is a central component of the pathogenesis of myonecrosis caused by Clostridium perfringens. The C. perfringens α-toxin has been shown capable of inducing these changes, but its potential synergy with perfringolysin O (θ-toxin) is less well underst...
Autores principales: | Hickey, Michael J., Kwan, Rain Y. Q., Awad, Milena M., Kennedy, Catherine L., Young, Lauren F., Hall, Pam, Cordner, Leanne M., Lyras, Dena, Emmins, John J., Rood, Julian I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275794/ https://www.ncbi.nlm.nih.gov/pubmed/18404211 http://dx.doi.org/10.1371/journal.ppat.1000045 |
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