Early Deletion and Late Positive Selection of T-Cells Expressing a Male-Specific Receptor in T-Cell Receptor Transgenic Mice

The ontogeny of T cells in T-cell receptor (TCR) transgenic mice, which express a transgenic αβ heterodimer, specific for the male (H-Y) antigen in association with H-2D(b), was determined. The transgenic α chain was expressed on about 10% of the fetal thymocytes on day 14 of gestation. About 50% of...

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Detalles Bibliográficos
Autores principales: Teh, Hung Sia, Kishi, Hiroyuki, Scott, Bernadette, Borgulya, Peter, Von Boehmer, Harald, Kisielow, Pawel
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275819/
https://www.ncbi.nlm.nih.gov/pubmed/2152099
http://dx.doi.org/10.1155/1990/18208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275819/
https://www.ncbi.nlm.nih.gov/pubmed/2152099
http://dx.doi.org/10.1155/1990/18208

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