Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size

Tadpole and adult Xenopus, manipulated to be of comparable size, exhibited stagespecific antibody expression. The production of adult-type higher-affinity anti-DNP antibodies proved to be independent of the age and size of the individual and is concomitant with the completion of metamorphosis. The a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsu, Ellen, Pasquier, Louis Du
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275844/
https://www.ncbi.nlm.nih.gov/pubmed/1521064
http://dx.doi.org/10.1155/1992/28568
_version_ 1782151917180289024
author Hsu, Ellen
Pasquier, Louis Du
author_facet Hsu, Ellen
Pasquier, Louis Du
author_sort Hsu, Ellen
collection PubMed
description Tadpole and adult Xenopus, manipulated to be of comparable size, exhibited stagespecific antibody expression. The production of adult-type higher-affinity anti-DNP antibodies proved to be independent of the age and size of the individual and is concomitant with the completion of metamorphosis. The appearance of new antibody specificities at such a time suggests that their expression occurs with the cell turnover and renewal during a period of morphological changes.
format Text
id pubmed-2275844
institution National Center for Biotechnology Information
language English
publishDate 1992
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-22758442008-03-31 Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size Hsu, Ellen Pasquier, Louis Du Dev Immunol Research Article Tadpole and adult Xenopus, manipulated to be of comparable size, exhibited stagespecific antibody expression. The production of adult-type higher-affinity anti-DNP antibodies proved to be independent of the age and size of the individual and is concomitant with the completion of metamorphosis. The appearance of new antibody specificities at such a time suggests that their expression occurs with the cell turnover and renewal during a period of morphological changes. Hindawi Publishing Corporation 1992 /pmc/articles/PMC2275844/ /pubmed/1521064 http://dx.doi.org/10.1155/1992/28568 Text en Copyright © 1992 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Hsu, Ellen
Pasquier, Louis Du
Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
title Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
title_full Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
title_fullStr Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
title_full_unstemmed Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
title_short Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
title_sort changes in the amphibian antibody repertoire are correlated with metamorphosis and not with age or size
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275844/
https://www.ncbi.nlm.nih.gov/pubmed/1521064
http://dx.doi.org/10.1155/1992/28568
work_keys_str_mv AT hsuellen changesintheamphibianantibodyrepertoirearecorrelatedwithmetamorphosisandnotwithageorsize
AT pasquierlouisdu changesintheamphibianantibodyrepertoirearecorrelatedwithmetamorphosisandnotwithageorsize

Ejemplares similares