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Induction of Apoptosis in Thymocytes by Prostaglandin E(2) In Vivo

In vivo administration in mice of a synthetic analog of prostaglandin E(2) (PGE(2)) caused a selective and dramatic decrease of CD4(+)CD8(+) double-positive, CD3/T-cell-receptor-αb(10) cells in the thymus. This loss was corticosteroid-independent and not affected by Cyclosporin A. The disappearance...

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Detalles Bibliográficos
Autores principales:	Mastino, Antonio, Piacentini, Mauro, Grelli, Sandro, Favalli, Cartesio, Autuori, Francesco, Tentori, Lucio, Oliverio, Serafina, Garach, Enrico
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1992
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275867/ https://www.ncbi.nlm.nih.gov/pubmed/1364176 http://dx.doi.org/10.1155/1992/80863

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