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IgH Diversity In an Individual With Only One Million B Lymphocytes

Immunoglobulin sequences from an individual Xenopus laevis froglet were analyzed for combinatorial and junctional diversity. In an animal with about 10(6) B lymphocytes, at least 26 out of the 56 V(H)1 genes available in a diploid genome were expressed, as were all J(H) segments. Junctional diversit...

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Detalles Bibliográficos
Autores principales: Lee, Ada, Desravines, Soléenne, Hsu, Ellen
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275927/
https://www.ncbi.nlm.nih.gov/pubmed/8281034
http://dx.doi.org/10.1155/1993/17249