Overusage of Mouse DH Gene Segment, DFL16.1, Is Strain-Dependent and Determined by cis-Acting Elements

The DJH structure is of particular importance for diversity in the immunoglobulin heavy chain because it encodes most of CDR3. Here, we investigate mechanisms responsible for generating the DJH structure. We found DFL16.1 was used at a high frequency in normal and transformed pre-B cells (fetal live...

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Detalles Bibliográficos
Autores principales: Atkinson, Michael J., Chang, Yenhui, Celler, Jakub W., Huang, Carol, Paige, Christopher J., Wu, Gillian E.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275935/
https://www.ncbi.nlm.nih.gov/pubmed/7620320
http://dx.doi.org/10.1155/1994/80207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275935/
https://www.ncbi.nlm.nih.gov/pubmed/7620320
http://dx.doi.org/10.1155/1994/80207

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