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Positive Selection by Purified MHC Class II / Thymic Epithelial Cells In Vitro: Costimulatory Signals Mediated by B7 Are Not Involved

We have investigated the possibility that the costimulatory signals required for activation of mature T cells also play a role in providing differentiation signals for positive selection during T-cell development. We show that purified MHC Class II(+) thymic epithelial cells are able to support posi...

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Detalles Bibliográficos
Autores principales:	Jenkinson, Eric J., Anderson, Graham, Moore, Nel C., Smith, Christopher A., Owen, John J. T.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1994
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275936/ https://www.ncbi.nlm.nih.gov/pubmed/7620318 http://dx.doi.org/10.1155/1994/75434

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