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Quantitative Analysis of the Efficiency of Clonal Deletion in the Thymus

One of the major mechanisms for establishing self-tolerance is the clonal deletion of self-reactive T cells during their development in the thymus. Using a TCR transgenic mouse model, we have established a quantitative ex vivo assay for examining the sensitivity and specificity of negative selection...

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Detalles Bibliográficos
Autores principales:	Spain, Lisa M., Berg, Leslie J.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1994
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275944/ https://www.ncbi.nlm.nih.gov/pubmed/7620325 http://dx.doi.org/10.1155/1994/92025

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