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Cross-Linking the TCR Complex Induces Apoptosis in CD4(+)8(+) Thymocytes in the Presence of Cyclosporin A

Although it is generally agreed that TCR ligation is a minimal requirement for negative selection in the CD(+)8(+) double-positive (DP) thymocyte subset, the costimulatory requirements and specific signaling events necessary to induce apoptosis are not well defined. We have explored the consequences...

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Detalles Bibliográficos
Autores principales:	Poetschke, Heather L., Klug, David B., Walker, Dawn, Richie, Ellen R.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1996
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275973/ https://www.ncbi.nlm.nih.gov/pubmed/8828007 http://dx.doi.org/10.1155/1996/57362

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