Thymic Stromal-Cell Abnormalities and Dysregulated T-Cell Development in IL-2-Deficient Mice

The role that interleukin-2 (IL-2) plays in T-cell development is not known. To address this issue, we have investigated the nature of the abnormal thymic development and autoimmune disorders that occurs in IL-2-deficient (IL-2(–/–)) mice. After 4 to 5 weeks of birth, IL-2(–/–) mice progressively de...

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Detalles Bibliográficos
Autores principales: Reya, Tannishtha, Bassiri, Hamid, Biancaniello, Renée, Carding, Simon R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275991/
https://www.ncbi.nlm.nih.gov/pubmed/9814585
http://dx.doi.org/10.1155/1998/19567

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