A Developmental Bias in Reading Frame Usage by Human Fetal Thymic TCRBDJ Transcripts is not Present in Genomic TCRBDJ Rearrangements

We have previously reported that reading-frame usage and functional diversification is developmentally regulated, with virtually all TCRB DJ mRNA transcripts using a single reading frame at 8 weeks of gestational age, tapering to 50% by adult life. We used the polymerase chain reaction to create gen...

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Detalles Bibliográficos
Autores principales: George, James F., Matsuura, Yasushi, Byrne, Jacquelyn A., Liu, Eugene L., Shaw, Denise R., Kearney, John F.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276035/
https://www.ncbi.nlm.nih.gov/pubmed/10636474
http://dx.doi.org/10.1155/1999/16178

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