Increased Thymic B Cells but Maintenance of Thymic Structure, T Cell Differentiation and Negative Selection in Lymphotoxin-α and TNF Gene-Targeted Mice

TNF, lymphotoxin (LT) and their receptors are expressed constitutively in the thymus. It remains unclear whether these cytokines play a role in normal thymic structure or function. We have investigated thymocyte differentiation, selection and thymic organogenesis in gene targeted mice lacking LTα, T...

Descripción completa

Detalles Bibliográficos
Autores principales: Grech, Adrian P., Riminton, D. Sean, Gabor, Melinda J., Hardy, Charles L., Sedgwick, Jonathon D., Godfrey, Dale I.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276063/
https://www.ncbi.nlm.nih.gov/pubmed/11293812
http://dx.doi.org/10.1155/2000/13492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276063/
https://www.ncbi.nlm.nih.gov/pubmed/11293812
http://dx.doi.org/10.1155/2000/13492

Ejemplares similares