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Role of Bruton's Tyrosine Kinase in B Cell Development

X-linked agammaglobulinemia (XLA) is one of the most frequent inherited immunodeficiency diseases in man and is characterized by an almost complete arrest of B cell differentiation at the pre-B cell stage. The gene defective in XLA encodes the cytoplasmic signaling molecule Bruton's tyrosine ki...

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Detalles Bibliográficos
Autores principales: Maas, Alex, Hendriks, Rudolf W.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276078/
https://www.ncbi.nlm.nih.gov/pubmed/11785667
http://dx.doi.org/10.1155/2001/28962