Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway

BACKGROUND: HIV triggers the decline of CD4(+ )T cells and leads to progressive dysfunction of cell-mediated immunity. Although an increased susceptibility to cell death occurs during the acute phase of HIV infection, persistently-infected macrophages and quiescent T-cells seem to be resistant to ce...

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Detalles Bibliográficos
Autores principales: Fernández Larrosa, Pablo N, Croci, Diego O, Riva, Diego A, Bibini, Mariel, Luzzi, Renata, Saracco, Mónica, Mersich, Susana E, Rabinovich, Gabriel A, Peralta, Liliana Martínez
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276517/
https://www.ncbi.nlm.nih.gov/pubmed/18261236
http://dx.doi.org/10.1186/1742-4690-5-19

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