Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum

BACKGROUND: Tuberculous sputum provides a sample of bacilli that must be eliminated by chemotherapy and that may go on to transmit infection. A preliminary observation that Mycobacterium tuberculosis cells contain triacylglycerol lipid bodies in sputum, but not when growing in vitro, led us to inves...

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Detalles Bibliográficos
Autores principales: Garton, Natalie J, Waddell, Simon J, Sherratt, Anna L, Lee, Su-Min, Smith, Rebecca J, Senner, Claire, Hinds, Jason, Rajakumar, Kumar, Adegbola, Richard A, Besra, Gurdyal S, Butcher, Philip D, Barer, Michael R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276522/
https://www.ncbi.nlm.nih.gov/pubmed/18384229
http://dx.doi.org/10.1371/journal.pmed.0050075

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