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Structure-Based Inhibitors Exhibit Differential Activities against Helicobacter pylori and Escherichia coli Undecaprenyl Pyrophosphate Synthases

Helicobacter pylori colonizes the human gastric epithelium and causes diseases such as gastritis, peptic ulcers, and stomach cancer. Undecaprenyl pyrophosphate synthase (UPPS), which catalyzes consecutive condensation reactions of farnesyl pyrophosphate with eight isopentenyl pyrophosphate to form l...

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Detalles Bibliográficos
Autores principales:	Kuo, Chih-Jung, Guo, Rey-Ting, Lu, I-Lin, Liu, Hun-Ge, Wu, Su-Ying, Ko, Tzu-Ping, Wang, Andrew H.-J., Liang, Po-Huang
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276626/ https://www.ncbi.nlm.nih.gov/pubmed/18382620 http://dx.doi.org/10.1155/2008/841312

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