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Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patie...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276692/ https://www.ncbi.nlm.nih.gov/pubmed/18382622 http://dx.doi.org/10.1155/2008/654987 |
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author | Singh, Rabindra P. Grimer, Robert J. Bhujel, Nabina Carter, Simon R. Tillman, Roger M. Abudu, Adesegun |
author_facet | Singh, Rabindra P. Grimer, Robert J. Bhujel, Nabina Carter, Simon R. Tillman, Roger M. Abudu, Adesegun |
author_sort | Singh, Rabindra P. |
collection | PubMed |
description | We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes. |
format | Text |
id | pubmed-2276692 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-22766922008-04-01 Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome Singh, Rabindra P. Grimer, Robert J. Bhujel, Nabina Carter, Simon R. Tillman, Roger M. Abudu, Adesegun Sarcoma Clinical Study We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes. Hindawi Publishing Corporation 2008 2008-03-18 /pmc/articles/PMC2276692/ /pubmed/18382622 http://dx.doi.org/10.1155/2008/654987 Text en Copyright © 2008 Rabindra P. Singh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Singh, Rabindra P. Grimer, Robert J. Bhujel, Nabina Carter, Simon R. Tillman, Roger M. Abudu, Adesegun Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome |
title | Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome |
title_full | Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome |
title_fullStr | Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome |
title_full_unstemmed | Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome |
title_short | Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome |
title_sort | adult head and neck soft tissue sarcomas: treatment and outcome |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276692/ https://www.ncbi.nlm.nih.gov/pubmed/18382622 http://dx.doi.org/10.1155/2008/654987 |
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