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Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome

We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patie...

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Autores principales: Singh, Rabindra P., Grimer, Robert J., Bhujel, Nabina, Carter, Simon R., Tillman, Roger M., Abudu, Adesegun
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276692/
https://www.ncbi.nlm.nih.gov/pubmed/18382622
http://dx.doi.org/10.1155/2008/654987
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author Singh, Rabindra P.
Grimer, Robert J.
Bhujel, Nabina
Carter, Simon R.
Tillman, Roger M.
Abudu, Adesegun
author_facet Singh, Rabindra P.
Grimer, Robert J.
Bhujel, Nabina
Carter, Simon R.
Tillman, Roger M.
Abudu, Adesegun
author_sort Singh, Rabindra P.
collection PubMed
description We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes.
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spelling pubmed-22766922008-04-01 Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome Singh, Rabindra P. Grimer, Robert J. Bhujel, Nabina Carter, Simon R. Tillman, Roger M. Abudu, Adesegun Sarcoma Clinical Study We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes. Hindawi Publishing Corporation 2008 2008-03-18 /pmc/articles/PMC2276692/ /pubmed/18382622 http://dx.doi.org/10.1155/2008/654987 Text en Copyright © 2008 Rabindra P. Singh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Singh, Rabindra P.
Grimer, Robert J.
Bhujel, Nabina
Carter, Simon R.
Tillman, Roger M.
Abudu, Adesegun
Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_full Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_fullStr Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_full_unstemmed Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_short Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_sort adult head and neck soft tissue sarcomas: treatment and outcome
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276692/
https://www.ncbi.nlm.nih.gov/pubmed/18382622
http://dx.doi.org/10.1155/2008/654987
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