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COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study

Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the −765G→C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the...

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Detalles Bibliográficos
Autores principales: Huuskonen, Kati H., Kunnas, Tarja A., Tanner, Minna M., Mikkelsson, Jussi, Ilveskoski, Erkki, Karhunen, Pekka J., Nikkari, Seppo T.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276816/
https://www.ncbi.nlm.nih.gov/pubmed/18385811
http://dx.doi.org/10.1155/2008/289453