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Statistical methodology for the analysis of dye-switch microarray experiments
BACKGROUND: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ensures an automatic correction of the gene-specific labelling bias, it also induces dependencies between log-ratio measurem...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277403/ https://www.ncbi.nlm.nih.gov/pubmed/18271965 http://dx.doi.org/10.1186/1471-2105-9-98 |