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An Unbiased Systems Genetics Approach to Mapping Genetic Loci Modulating Susceptibility to Severe Streptococcal Sepsis

Striking individual differences in severity of group A streptococcal (GAS) sepsis have been noted, even among patients infected with the same bacterial strain. We had provided evidence that HLA class II allelic variation contributes significantly to differences in systemic disease severity by modula...

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Detalles Bibliográficos
Autores principales: Abdeltawab, Nourtan F., Aziz, Ramy K., Kansal, Rita, Rowe, Sarah L., Su, Yin, Gardner, Lidia, Brannen, Charity, Nooh, Mohammed M., Attia, Ramy R., Abdelsamed, Hossam A., Taylor, William L., Lu, Lu, Williams, Robert W., Kotb, Malak
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277464/
https://www.ncbi.nlm.nih.gov/pubmed/18421376
http://dx.doi.org/10.1371/journal.ppat.1000042